Vivace Therapeutics Strengthens Leadership Team as It Prepares to Advance VT3989, the First TEAD Inhibitor to enter Phase 3 Clinical Trials, as the Leading Treatment for Mesothelioma
New Clinical Data for Vivace Therapeutics’ Best-in-Class, Hippo Pathway-Targeting Therapy to be Presented in Oral Presentation at the European Society for Medical Oncology (ESMO) Congress 2025
Researchers Report Clinical Proof-of-Concept Data for Vivace Therapeutics’ VT3989, a First for a Cancer Drug Targeting the Hippo Pathway, in Oral Presentation at AACR 2023
Vivace Therapeutics Presents New Preclinical Data Highlighting Strong Synergistic Activity for Combination of VT3989 and Osimertinib at American Association for Cancer Research (AACR) Annual Meeting 2022
First-in-class, first-in-human phase 1 trial of VT3989, an inhibitor of Yes-Associated Protein (YAP)/Transcriptional Enhancer Activator Domain (TEAD), in patients with advanced solid tumors enriched for malignant mesothelioma and other tumors with neurofibromatosis 2 (NF2) mutations
VT3989, a clinical TEAD palmitoylation inhibitor, enhances the efficacy and durability of multiple targeted therapies of the MAPK and PI3K/AKT/mTOR pathways
The TEAD autopalmitoylation inhibitor VT3989 improves efficacy and increases durability of efficacy of osimertinib in preclinical EGFR mutant tumor models
